Evidence of higher oxidative status in depression and anxiety

This 2014 paper measured the urinary redox potential of urine, which is a simple method for evaluating antioxidative status, with the aim to analyse the global antioxidative status and to correlate these findings with measures of anxiety and depression in 63 individuals (28 male, 35 females, ages 20-65). Normal anxiety state values corresponded to low urine redox potentials whereas higher anxiety states were associated with high urinary redox potential indicating high oxidative stress. It was also found that those with normal values in terms of the validated Beck Depression Inventory (BDI) questionnaire (used to assess anxiety and depression) had significantly lower urine redox potentials than individuals with higher BDI values. The results suggest that individuals with depression and anxiety are deficient in antioxidants, indicative of oxidative stress. [NPID: antioxidative status, antioxidants, anxiety, depression, oxidative stress]

Year: 2014

Reference: Grases, G., Colom, M. A., Fernandez, R. A., Costa-Bauzá, A., & Grases, F. (2014). Evidence of higher oxidative status in depression and anxiety. Oxidative medicine and cellular longevity, 2014, 430216. https://doi.org/10.1155/2014/430216

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