Mind-altering with the gut: Modulation of the gut-brain axis with probiotics

This 2018 review explored the role of gut microbiota in bidirectional interactions between the gut and the brain, including neural, immune-mediated, and metabolic mechanisms. Recent preclinical and clinical trials revealed that gut microbiota plays an important role in the bidirectional interactions between the gastrointestinal tract, the enteric nervous system, and the central nervous system, which is alarming since alterations in gut microbiota composition may be associated with pathogenesis of various neurological disorders, including stress, autism, depression, Parkinson’s disease, and Alzheimer’s disease. Kim et al. (2018) also highlighted recent advances in the understanding of probiotic modulation of neurological and neuropsychiatric disorders. [NPID: psychiatric illnesses, MGBA, gut-brain axis, gut microbiome, enteric nervous system, neurological disorders, stress, autism, depression, Parkinson’s disease, Alzheimer’s disease]

Year: 2018

Reference: Kim, N., Yun, M., Oh, Y. J., & Choi, H. J. (2018). Mind-altering with the gut: Modulation of the gut-brain axis with probiotics. Journal of microbiology (Seoul, Korea), 56(3), 172–182. https://doi.org/10.1007/s12275-018-8032-4

Related Studies

Extra-virgin olive oil and the gut-brain axis: influence on gut microbiota, mucosal immunity, and cardiometabolic and cognitive health

Extra-virgin olive oil (EVOO) is a well-liked functional food and an essential fat source in Mediterranean diets, containing several beneficial ingredients such as bioactive phenolic compounds and monounsaturated fatty acids, which individually and together have positive effects on cardiometabolic health markers and function as neuroprotective agents due to their antioxidant and anti-inflammatory properties. Through the […]

Gut microbiota and inflammatory factor characteristics in major depressive disorder patients with anorexia

In this study by Guo et al. (2024), the authors examined the gut microbiota and inflammatory variables in anorexic major depressive disorder (MDD) patients and the connections between HAMD scores, anorexia, inflammatory factors, and gut microbiota. The authors recruited 46 individuals with major depressive disorder and an equal number of healthy controls. Among the MDD […]